Zeiler K, Auff E, Schnaberth G
Wien Klin Wochenschr. 1984 Aug 3;96(15):580-4.
46 patients (aged 13 to 40 years) suffering from ischaemic cerebrovascular disease were investigated by means of complete 4-vessel angiography. 40 of these patients were re-examined after a mean follow-up period of 57 months. The aim of the study was to investigate possible connections between the angiographic data and the clinical condition some years later. In the 37 patients who were not subjected to surgical treatment prognosis was not significantly different in cases with, and those without stenoses/occlusions in the craniocervical vessels. However, patients suffering from severe stenoses/occlusions had a significantly worse prognosis than patients with stenoses of a mild degree. The clinical course in patients with stenoses/occlusions localized in the vertebro-basilar system was significantly more favourable than the course of the disease in patients with similar changes in the carotid system. There was a trend towards a worse clinical picture at the end of the follow-up period in cases with degenerative alterations in the small intracranial arteries. The difference in prognostic value of cerebral 4-vessel angiography in cases of stroke in the young, as opposed to the findings in older patients is discussed.
对46例年龄在13至40岁之间的缺血性脑血管疾病患者进行了全脑四血管造影检查。其中40例患者在平均随访57个月后接受了复查。本研究的目的是调查血管造影数据与数年后临床状况之间可能存在的联系。在未接受手术治疗的37例患者中,颅颈血管有狭窄/闭塞和无狭窄/闭塞的患者预后无显著差异。然而,患有严重狭窄/闭塞的患者预后明显比轻度狭窄患者差。椎基底系统存在狭窄/闭塞的患者临床病程明显比颈动脉系统有类似病变的患者更有利。颅内小动脉发生退行性改变的患者在随访期末有临床症状恶化的趋势。文中讨论了脑四血管造影在年轻卒中患者中的预后价值差异,与老年患者的研究结果形成对比。