在南非德班分离出的产青霉素酶和不产青霉素酶的淋病奈瑟菌菌株的体外抗菌药敏性。
In vitro antimicrobial susceptibilities of penicillinase-producing and non-penicillinase-producing strains of Neisseria gonorrhoeae isolated in Durban, South Africa.
作者信息
Coovadia Y M, Ramsaroop U
出版信息
Antimicrob Agents Chemother. 1984 Nov;26(5):770-2. doi: 10.1128/AAC.26.5.770.
Abstract
The in vitro susceptibilities of 22 penicillinase-producing and 32 non-penicillinase-producing strains of Neisseria gonorrhoeae to 13 antimicrobial agents, including the new semisynthetic penicillins and cephalosporins, are reported. Ceftriaxone, ceftazidime, and cefotaxime were the most active agents tested; none of them had an MIC of greater than 0.03 micrograms/ml. Amoxycillin plus clavulanic acid and temocillin also showed good activity against both strains of gonococci.
摘要
报告了22株产青霉素酶和32株不产青霉素酶的淋病奈瑟菌对13种抗菌剂的体外敏感性，这些抗菌剂包括新型半合成青霉素和头孢菌素。头孢曲松、头孢他啶和头孢噻肟是测试中活性最强的药物；它们的最低抑菌浓度均不超过0.03微克/毫升。阿莫西林加克拉维酸和替莫西林对两种淋病奈瑟菌菌株也显示出良好的活性。
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