In vitro activity of Ro 15-8074, a new oral cephalosporin, against Neisseria gonorrhoeae.
作者信息
Ng W S, Chau P Y, Leung Y K, Wong P C
出版信息
Antimicrob Agents Chemother. 1985 Sep;28(3):461-3. doi: 10.1128/AAC.28.3.461.
Abstract
Ro 15-8074, a new cephalosporin the pivaloyloxymethylester of which (Ro 15-8075) is orally absorbable, showed greater in vitro activity than cefaclor against 48 Neisseria gonorrhoeae strains, including 25 penicillinase-producing strains. Unlike cefaclor, Ro 15-8074 was unaffected by increase in inoculum size, and it exhibited a remarkable stability against gonococcal beta-lactamase hydrolysis.
摘要
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