实验性胎儿窘迫期间连续代谢监测的趋势

Trends in continuous metabolic monitoring during experimental fetal distress.

作者信息

Abitbol M M, La Gamma E F

出版信息

Am J Perinatol. 1984 Jul;1(4):293-7. doi: 10.1055/s-2007-1000024.

DOI:10.1055/s-2007-1000024

Abstract

Intermittent, progressive maternal aortic occlusions were used to produce fetal distress in the fetuses of six pregnant dogs at term. Fetal heart rate and fetal tissue surface pH were continuously recorded and were compared to fetal blood pH, pCO2, pO2 and lactic acid values determined from intermittent sampling. Baseline fetal heart rate was an insensitive indicator of fetal blood pH, tissue surface pH, or of fetal blood lactic acid concentrations. "Delayed" decelerations in fetal heart rate following an occlusive episode were uniformly produced after minimal stress and also did not correlate well with these variables. On the other hand, fetal blood lactic acid concentrations remained elevated even after occlusive episodes were discontinued and other variables had returned to baseline values.

摘要

对6只足月妊娠母犬采用间歇性、渐进性的母体主动脉闭塞法，以使胎儿出现窘迫。持续记录胎儿心率和胎儿组织表面pH值，并与通过间歇性采样测定的胎儿血液pH值、pCO2、pO2和乳酸值进行比较。胎儿心率基线对胎儿血液pH值、组织表面pH值或胎儿血液乳酸浓度而言，是一个不敏感的指标。闭塞发作后胎儿心率出现的“延迟”减速在最小应激后均会出现，且与这些变量的相关性也不佳。另一方面，即使在闭塞发作停止且其他变量已恢复至基线值后，胎儿血液乳酸浓度仍持续升高。