Väänänen H K
Histochemistry. 1984;81(5):485-7. doi: 10.1007/BF00489754.
Carbonic anhydrase isoenzymes I and II have been localized in human bone and cartilage. Osteoclasts are strongly positive for carbonic anhydrase II but very little if any reaction is observed for carbonic anhydrase I. In tendon giant cell tumor osteoclastlike-giant cells contained high amounts of carbonic anhydrase II suggesting the close relation of these cells to normal osteoclasts. In growth plate cartilage strong staining was obtained in late proliferative and hypertrophic chondrocytes as well as in extracellular matrix of hypertrophic zone also only with anti-human carbonic anhydrase II.
碳酸酐酶同工酶I和II已定位在人类骨骼和软骨中。破骨细胞对碳酸酐酶II呈强阳性，但对碳酸酐酶I几乎没有反应（如果有反应也是极少的）。在腱鞘巨细胞瘤中，破骨细胞样巨细胞含有大量的碳酸酐酶II，表明这些细胞与正常破骨细胞关系密切。在生长板软骨中，仅用抗人碳酸酐酶II抗体，在增殖后期和肥大软骨细胞以及肥大区的细胞外基质中获得了强染色。
