van Riel P L, van de Putte L B, Gribnau F W, de Waal R M
Scand J Rheumatol. 1984;13(4):334-6. doi: 10.3109/03009748409111305.
A 43-year-old woman with seronegative rheumatoid arthritis developed a selective IgA deficiency during aurothioglucose treatment. No antibodies against IgA were detectable in the serum; normal numbers of IgA, IgG and IgM positive cells were demonstrated by immunofluorescence studies on a biopsy specimen from the small intestine. These data would suggest a defect in IgA secretion rather than in production by plasma cells.
一名43岁血清阴性类风湿性关节炎女性在接受金硫葡萄糖治疗期间出现选择性IgA缺乏。血清中未检测到抗IgA抗体；通过对小肠活检标本进行免疫荧光研究，显示IgA、IgG和IgM阳性细胞数量正常。这些数据表明是IgA分泌存在缺陷，而非浆细胞产生存在缺陷。
