Haldorsen T, Aarli J A
Acta Neurol Scand. 1977 Dec;56(6):608-12. doi: 10.1111/j.1600-0404.1977.tb01466.x.
Serum immunoglobulins A, G and M were studied in parents and siblings of 16 patients being treated for epilepsy. Five healthy families served as controls. Seven of the patients were low IgA-responders and the rest of the patients had shown normal IgA-levels during treatment. None of the parents and siblings studied showed a serum-IgA deficiency, with the exception of one mother who was being treated for rheumatoid arthritis with naproxen. Low serum concentrations of IgG and IgM were not found. A significantly increased IgM-level was found in first-degree relatives of the low IgA-responders, and the siblings of low 2gA-responders had significantly raised IgA in their sera.
对16名正在接受癫痫治疗的患者的父母及兄弟姐妹的血清免疫球蛋白A、G和M进行了研究。选取5个健康家庭作为对照。7名患者为低IgA反应者，其余患者在治疗期间IgA水平正常。除一名正在用萘普生治疗类风湿性关节炎的母亲外，所研究的父母及兄弟姐妹均未出现血清IgA缺乏。未发现血清IgG和IgM浓度降低。在低IgA反应者的一级亲属中发现IgM水平显著升高，低IgA反应者的兄弟姐妹血清中IgA显著升高。
