Breslow L
Science. 1978 May 26;200(4344):908-12. doi: 10.1126/science.644333.
Risk factors for disease consist of (i) personal habits, such as cigarette smoking and excessive alcohol consumption, and (ii) bodily characteristics, such as hypertension and high serum cholesterol. Progress in identifying and quantifying risk factors is opening the way to the prevention of disease and maintenance of health. Systematic, controlled trials of intervention against risk factors are beginning to produce evidence on the extent of success in reducing both the factors and the mortality from associated diseases.
(i)个人习惯,如吸烟和过量饮酒;(ii)身体特征,如高血压和高血清胆固醇。在识别和量化风险因素方面取得的进展为疾病预防和健康维持开辟了道路。针对风险因素进行干预的系统、对照试验开始产生证据,证明在降低这些因素以及相关疾病死亡率方面取得成功的程度。