Svandová E, Stastná J, Kubín M
J Hyg Epidemiol Microbiol Immunol. 1984;29(3):275-81.
Comparative skin tests with 2 TU PPD-RT 23 with Tween 80 (prepared from M. tuberculosis) and 5 TU PPD-RS 95 with Tween 80 (prepared from M. scrofulaceum) were intradermally given to a total of 1,140 7-year-old children in two towns of Karviná district (340 and 255 children) and in Teplice (267 children) and Prague (278 children). In the two groups of Karviná district children the percentages of small-sized reactions (6-9 mm) to PPD-RT 23 were 13.6 and 22.3% compared to 7.1% in Teplice and 5.7% in Prague. The prevalence of small reactions to the PPD-RS 95 test in district of Karviná was 14.4 and 16.9%, in Teplice 4.5% and in Prague 6.8%. In the two towns of Karviná district the percentages of children whose reaction to PPD-RS 95 was larger than to PPD-RT 23 were 56.4 and 42.8%, in Teplice 24% and in Prague 24%. The hypothesis is advanced that the higher degree of skin hypersensitivity to the M. scrofulaceum mycobacterin which was found among the Karviná district children tested is due to sensitization with environmental mycobacteria which are common in this area.
对卡尔维纳区两个城镇（分别为340名和255名儿童）、特普利采（267名儿童）和布拉格（278名儿童）的总共1140名7岁儿童进行了皮内比较皮肤试验，分别注射含吐温80的2 TU PPD - RT 23（由结核分枝杆菌制备）和含吐温80的5 TU PPD - RS 95（由瘰疬分枝杆菌制备）。在卡尔维纳区两组儿童中，对PPD - RT 23出现小尺寸反应（6 - 9毫米）的百分比分别为13.6%和22.3%，而在特普利采为7.1%，在布拉格为5.7%。卡尔维纳区对PPD - RS 95试验出现小反应的患病率分别为14.4%和16.9%，在特普利采为4.5%，在布拉格为6.8%。在卡尔维纳区的两个城镇中，对PPD - RS 95反应大于对PPD - RT 23反应的儿童百分比分别为56.4%和42.8%，在特普利采为24%，在布拉格为24%。由此提出一个假设，即在接受测试的卡尔维纳区儿童中发现的对瘰疬分枝杆菌菌素的皮肤超敏反应程度较高，是由于该地区常见的环境分枝杆菌致敏所致。
