Modified neurosyphilis in the Cape Peninsula.

A prospective study of 148 cases of neurosyphillis revealed that 85 patients exhibited a modified 'forme fruste' of the disease. A high proportion of these patients had evidence of activity in the cerebrospinal fluid, while 6 patients have developed features which are diagnostic of neurosyphills. During the study a significant number of active seronegative cases were diagnosed and 11 patients have deteriorated on treatment.