Sands M
JAMA. 1980 Mar 21;243(11):1143-4.
The charts of 606 men with anorectal gonorrhea infections treated using the current Public Health Service recommendations were reviewed. There were 3.3% failures in the group treated with penicillin--14.4% in those treated with tetracycline hydrochloride, 14.8% in the ampicillin trihydrate group, and none among those treated with spectinomycin hydrochloride. The intramuscular (IM) injection of penicillin G procaine, 4.8 million units, with 1 g of probenicid given orally is the treatment of choice for anorectal gonorrhea. An IM injection of 2 g of spectinomycin hydrochloride was effective but should be reserved for patients allergic to penicillin and for penicillin treatment failures.
对606名按照当前公共卫生服务建议治疗的肛门直肠淋病感染男性患者的病历进行了回顾。青霉素治疗组的失败率为3.3%，盐酸四环素治疗组为14.4%，三水合氨苄西林组为14.8%，而盐酸大观霉素治疗组无一例失败。肌内注射480万单位普鲁卡因青霉素G并口服1克丙磺舒是肛门直肠淋病的首选治疗方法。肌内注射2克盐酸大观霉素有效，但应留作青霉素过敏患者和青霉素治疗失败患者使用。
