男性肛门直肠淋病的治疗。口服抗生素方案的疗效。
Therapy of anorectal gonorrhea in men. Efficacy of oral antibiotic regimens.
作者信息
Sands M, Sellers T
出版信息
West J Med. 1980 Dec;133(6):469-71.
The results of therapy in 916 men with anorectal gonorrhea treated with orally given antibiotic drugs were reviewed retrospectively. There was a 17.8 percent failure rate for tetracycline (total dose, 10 grams) and a 10.7 percent failure for 3.5 grams of ampicillin plus 1 gram of probenicid. Repeating the ampicillin plus probenicid dose once in 8 to 14 hours reduced the failure rate to 1.6 percent, an efficacy comparable to the regimen of 4.8 million units of aqueous procaine penicillin G given intramuscularly plus 1 gram of probenicid given orally for treatment of anorectal gonorrhea.
对916例口服抗生素治疗的男性肛门直肠淋病患者的治疗结果进行了回顾性分析。四环素（总剂量10克）的失败率为17.8%，3.5克氨苄西林加1克丙磺舒的失败率为10.7%。每8至14小时重复一次氨苄西林加丙磺舒剂量可将失败率降至1.6%，其疗效与肌内注射480万单位普鲁卡因青霉素G加口服1克丙磺舒治疗肛门直肠淋病的方案相当。
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