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人类妊娠中的淋巴细胞介导的细胞毒性和体液抗体

Lymphocyte-mediated cytotoxicity and humoral antibodies in human pregnancy.

作者信息

Chardonnens X, Jeannet M

出版信息

Int Arch Allergy Appl Immunol. 1980;61(4):467-71. doi: 10.1159/000232475.

DOI:10.1159/000232475
PMID:6444927
Abstract

Lymphocyte-mediated cytotoxicity, antibody-dependent cell cytotoxicity and complement-dependent antibody assays were used to study maternal immune response to fetal antigens present on cord lymphocytes at delivery. Among 24 cell-mediated lympholysis tests, 4 were found slightly positive and accompanied by a complement-dependent antibody and/or an antibody-dependent cell cytotoxicity response. The humoral immune response was found more often positive than the cellular response.

摘要

采用淋巴细胞介导的细胞毒性、抗体依赖细胞的细胞毒性和补体依赖抗体检测，研究分娩时母体对脐淋巴细胞上存在的胎儿抗原的免疫反应。在24次细胞介导的淋巴细胞溶解试验中，发现4次呈弱阳性，并伴有补体依赖抗体和/或抗体依赖细胞的细胞毒性反应。发现体液免疫反应比细胞免疫反应更常呈阳性。

相似文献

1
Lymphocyte-mediated cytotoxicity and humoral antibodies in human pregnancy.人类妊娠中的淋巴细胞介导的细胞毒性和体液抗体
Int Arch Allergy Appl Immunol. 1980;61(4):467-71. doi: 10.1159/000232475.
2
Phenotypic and cytotoxic characteristics of the immune cells of the human placenta.人胎盘免疫细胞的表型和细胞毒性特征
Cell Immunol. 1986 Feb;97(2):335-43. doi: 10.1016/0008-8749(86)90404-1.
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Development of cell-mediated lympholysis in human foetal blood lymphocytes.人胎儿血淋巴细胞中细胞介导的淋巴细胞溶解作用的发展
Clin Exp Immunol. 1980 Dec;42(3):561-70.
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Humoral and cellular immunity to paternal antigens in trophoblastic neoplasia.滋养细胞肿瘤中针对父源抗原的体液免疫和细胞免疫。
Int J Cancer. 1979 Nov 15;24(5):586-93. doi: 10.1002/ijc.2910240511.
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Cytotoxicity of human peripheral lymphocytes in cell-mediated lympholysis; antibody-dependent cell-mediated lympholysis and natural cytotoxicity assays after mixed lymphocyte culture.细胞介导性淋巴细胞溶解中人类外周淋巴细胞的细胞毒性；混合淋巴细胞培养后的抗体依赖性细胞介导的细胞毒性及自然细胞毒性检测
J Immunol. 1978 Jul;121(1):81-5.
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Neonatal lymphocytes dominate against lymphocytes of their own mother but not against allogenic maternal or adult lymphocytes in bidirectional mixed lymphocyte cultures.在双向混合淋巴细胞培养中，新生儿淋巴细胞对其自身母亲的淋巴细胞具有优势，但对同种异体母亲或成人淋巴细胞则不然。
Fetal Diagn Ther. 2003 May-Jun;18(3):154-9. doi: 10.1159/000069369.
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A functional assay of HLA-directed non-T-cell mediated lympholysis (CML).HLA 定向的非 T 细胞介导的淋巴细胞溶解（CML）功能测定。
Transplant Proc. 1978 Dec;10(4):943-6.
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Development of the immune response.
Clin Allergy. 1973 Dec;3 Suppl:559-70. doi: 10.1111/j.1365-2222.1973.tb03061.x.
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Immune response in rabbits to surface components of extracellular and intracellular forms of vaccinia virus.兔对细胞外和细胞内形式痘苗病毒表面成分的免疫反应。
Infect Immun. 1980 Sep;29(3):846-52. doi: 10.1128/iai.29.3.846-852.1980.

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