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[缺血性心脏病中的昼夜脂质节律紊乱]

[Disorder of circadian lipid rhythms in ischemic heart disease].

作者信息

Ganelina I E, Aslanian N L, Babaian L A, Krivoruchenko I V, Shukhian V M

出版信息

Kardiologiia. 1980 Mar;20(3):80-4.

PMID:6445437
Abstract

Thirty-six healthy males and 157 males with ischemic heart disease were examined. Healthy males had statistically significant changes in the daily rhythm of cholesterol, triglycerides, glucose, and total blood serum lipids, while the rhythms of nonesterified fatty acids, total phospholipids, and overall content of beta- and pre-beta-lipoproteins were statistically insignificant. Patients with ischemic heart disease had statistically significant rhythms of cholesterol, triglycerides, total lipids, and total phospholipids, while the daily rhythms of nonesterified fatty acids, glucose and the overall content of beta- and pre-beta-lipoproteins in blood serum were statistically insignificant. Desynchronization of the acrophase of the daily rhythm of the overall content of beta-and pre-beta-lipoproteins as compared to the findings in healthy individuals was encountered.

摘要

对36名健康男性和157名缺血性心脏病男性进行了检查。健康男性的胆固醇、甘油三酯、葡萄糖和血清总脂质的日节律有统计学显著变化,而游离脂肪酸、总磷脂以及β-脂蛋白和前β-脂蛋白的总含量的节律无统计学意义。缺血性心脏病患者的胆固醇、甘油三酯、总脂质和总磷脂的节律有统计学显著意义,而血清中游离脂肪酸、葡萄糖以及β-脂蛋白和前β-脂蛋白的总含量的日节律无统计学意义。与健康个体的结果相比,发现β-脂蛋白和前β-脂蛋白总含量的日节律的峰相位不同步。

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