Majeron M A, Ambrosoli C, Armocida G, Finavera L, Quisi Q
Minerva Med. 1980 Apr 21;71(16):1213-20.
The Authors, referring to the actual biochemical hypotheses of the Chorea of Huntington and on the new prospects of treatment, report the experimental data relative to some therapeutic attempt on patients suffering from this disease. In two cases has been tested Bromocriptine, in three cases Bromocriptine with l-dopa, in three cases Piribedil with l-dopa, in four cases Haloperidol with l-dopa. Positive results of temporary term are obtained only with the association Piribedil plus l-dopa and in one case with the association Haloperidol plus l-dopa. The results are considered insufficient for assuming significance of clinical proposal.
作者们参考了亨廷顿舞蹈症的实际生化假说以及新的治疗前景，报告了关于对患有该疾病患者的一些治疗尝试的实验数据。在两例患者中测试了溴隐亭，三例患者中测试了溴隐亭与左旋多巴联用，三例患者中测试了匹莫齐特与左旋多巴联用，四例患者中测试了氟哌啶醇与左旋多巴联用。仅匹莫齐特加左旋多巴的联合用药以及一例氟哌啶醇加左旋多巴的联合用药取得了短期的阳性结果。这些结果被认为不足以支持临床建议的有效性。
