细胞毒性T细胞的体外分化。II. 针对K/D刺激在初次混合淋巴细胞培养物中产生的扩增因子需要Lyt 2+细胞存在，但不需要Lyt 1+细胞。 - Suppr

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超能文献

The differentiation of cytotoxic T cells in vitro. II. Amplifying factor(s) produced in primary mixed lymphocyte cultures against K/D stimuli require the presence of Lyt 2+ cells but not Lyt 1+ cells.

作者信息

Okada M, Henney C S

出版信息

J Immunol. 1980 Jul;125(1):300-7.

PMID:6445920

Abstract

摘要

相似文献

The differentiation of cytotoxic T cells in vitro. II. Amplifying factor(s) produced in primary mixed lymphocyte cultures against K/D stimuli require the presence of Lyt 2+ cells but not Lyt 1+ cells.细胞毒性T细胞的体外分化。II. 针对K/D刺激在初次混合淋巴细胞培养物中产生的扩增因子需要Lyt 2+细胞存在，但不需要Lyt 1+细胞。

J Immunol. 1980 Jul;125(1):300-7.

The differentiation of cytotoxic T cells in vitro. I. Amplifying factor(s) in the primary response is Lyt 1 + cell dependent.细胞毒性T细胞的体外分化。I. 初次应答中的扩增因子依赖于Lyt 1 + 细胞。

J Immunol. 1979 Jun;122(6):2527-33.

Suppression of cytotoxic lymphocyte responses in vitro by soluble products of alloantigen-activated spleen cells.同种异体抗原激活的脾细胞可溶性产物对体外细胞毒性淋巴细胞反应的抑制作用。

J Immunol. 1978 Sep;121(3):1045-51.

Limiting dilution analysis of alloantigen-reactive T lymphocytes. V. Lyt phenotype of cytolytic T lymphocyte precursors reactive against normal and mutant H-2 antigens.同种抗原反应性T淋巴细胞的有限稀释分析。V. 对正常和突变H-2抗原产生反应的细胞毒性T淋巴细胞前体的Lyt表型

J Immunol. 1981 Feb;126(2):490-6.

Lyt 1 cells respond to Ia-bearing macrophages in the murine syngeneic mixed lymphocyte reaction.在小鼠同基因混合淋巴细胞反应中，Lyt 1细胞对携带Ia抗原的巨噬细胞产生反应。

Eur J Immunol. 1980 Sep;10(9):723-6. doi: 10.1002/eji.1830100913.

T-T cell interactions during in vitro cytotoxic T lymphocyte (CTL) responses. II. Helper factor from activated Lyt 1+ T cells is rate limiting i) in T cell responses to nonimmunogenic alloantigen, ii) in thymocyte responses to allogeneic stimulator cells, and III) recruits allo- or H-2-restricted CTL precursors from the Lyt 123+ T subset.体外细胞毒性T淋巴细胞（CTL）应答过程中的T - T细胞相互作用。II. 活化的Lyt 1⁺ T细胞产生的辅助因子是以下情况的限速因素：i）T细胞对非免疫原性同种异体抗原的应答；ii）胸腺细胞对同种异体刺激细胞的应答；iii）从Lyt 123⁺ T亚群募集同种异体或H - 2限制性CTL前体。

J Immunol. 1980 Mar;124(3):1058-67.

The differentiation of cytotoxic T cells in vitro. III. The role of helper T cells and their products in the differentiation of cytotoxic cells from "memory" cell populations.细胞毒性T细胞的体外分化。III. 辅助性T细胞及其产物在“记忆”细胞群体中细胞毒性细胞分化中的作用。

J Immunol. 1980 Aug;125(2):850-7.

The differentiation of cytotoxic T cells in vitro. IV. Interleukin-2 production in primary mixed lymphocyte cultures involves cooperation between Qa-1+ and Qa-1- "helper" T cells.细胞毒性T细胞的体外分化。IV. 原代混合淋巴细胞培养中白细胞介素-2的产生涉及Qa-1 +和Qa-1 - “辅助”T细胞之间的合作。

J Immunol. 1981 Apr;126(4):1635-9.

Cellular origins of co-stimulator (IL2) and its activity in cytotoxic T lymphocyte responses.共刺激因子（IL2）的细胞起源及其在细胞毒性T淋巴细胞反应中的活性。

J Immunol. 1980 May;124(5):2231-9.

Enhancement of T. lymphocyte functions by Fc fragments of immunoglobulin. II. Augmentation of the cell-mediated lympholysis response occurs through an Lyt-1+2- helper T cell.免疫球蛋白Fc片段对T淋巴细胞功能的增强作用。II. 通过Lyt-1+2-辅助性T细胞增强细胞介导的淋巴细胞溶解反应。

J Immunol. 1981 Dec;127(6):2526-30.

引用本文的文献

Activation of natural killer (NK) cells in vivo with H-2 and non-H-2 alloantigens.用H-2和非H-2同种异体抗原在体内激活自然杀伤（NK）细胞。

Immunogenetics. 1981;12(3-4):221-35. doi: 10.1007/BF01561666.

Clonal analysis of human cytotoxic T lymphocytes: T4+ and T8+ effector T cells recognize products of different major histocompatibility complex regions.人细胞毒性T淋巴细胞的克隆分析：T4 +和T8 +效应T细胞识别不同主要组织相容性复合体区域的产物。

Proc Natl Acad Sci U S A. 1982 Jul;79(14):4395-9. doi: 10.1073/pnas.79.14.4395.

Long-term human cytolytic T-cell lines allospecific for HLA-DR6 antigen are OKT4+.对HLA - DR6抗原具有同种特异性的长期人类细胞溶解T细胞系为OKT4阳性。

Proc Natl Acad Sci U S A. 1982 Apr;79(7):2365-9. doi: 10.1073/pnas.79.7.2365.

Significance of Lyt phenotypes: Lyt2 antibodies block activities of T cells that recognize class 1 major histocompatibility complex antigens regardless of their function.Lyt表型的意义：Lyt2抗体可阻断识别1类主要组织相容性复合体抗原的T细胞的活性，无论其功能如何。

Proc Natl Acad Sci U S A. 1981 Nov;78(11):7101-5. doi: 10.1073/pnas.78.11.7101.

Interaction between MHC-encoded products and cloned T cells. II. Analyses of physiological requirements indicate two different pathways of stimulation by class I alloantigens.MHC编码产物与克隆化T细胞之间的相互作用。II. 生理需求分析表明I类同种异体抗原存在两种不同的刺激途径。

Immunogenetics. 1984;19(4):279-94. doi: 10.1007/BF00345401.

Cytotoxic T cells both produce and respond to interleukin 2.细胞毒性T细胞既能产生白细胞介素2，又能对其做出反应。

J Exp Med. 1984 Feb 1;159(2):647-52. doi: 10.1084/jem.159.2.647.

Alloreactive T-cell clones. Ly phenotypes predict both function and specificity for major histocompatibility complex products.同种反应性T细胞克隆。Ly表型可预测对主要组织相容性复合体产物的功能和特异性。

Immunogenetics. 1983;17(2):147-65. doi: 10.1007/BF00364755.

Lysis of tumor biopsy cells by autologous T lymphocytes activated in mixed cultures and propagated with T cell growth factor.通过在混合培养物中激活并与T细胞生长因子一起增殖的自体T淋巴细胞对肿瘤活检细胞进行裂解。

J Exp Med. 1982 Jan 1;155(1):83-95. doi: 10.1084/jem.155.1.83.

Enhancement of T lymphocyte functions by Fc fragments of immunoglobulins. I. Augmentation of allogeneic mixed lymphocyte culture reactions requires I-A- or I-B-subregion differences between effector and stimulator cell populations.免疫球蛋白Fc片段对T淋巴细胞功能的增强作用。I. 同种异体混合淋巴细胞培养反应的增强需要效应细胞和刺激细胞群体之间存在I-A或I-B亚区差异。

J Exp Med. 1981 May 1;153(5):1161-72. doi: 10.1084/jem.153.5.1161.

Interleukin 2: biology and biochemistry.白细胞介素2：生物学与生物化学

J Clin Immunol. 1983 Jan;3(1):1-13. doi: 10.1007/BF00919133.

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