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[代偿性心脏功能亢进关键阶段的心肌结缔组织成分]

[Myocardial connective tissue component in the critical stage of compensatory cardiac hyperfunction].

作者信息

Chervova I A, Pistsova T V, Zamaraeva E V

出版信息

Biull Eksp Biol Med. 1980 Mar;89(3):356-7.

PMID:6446332
Abstract

The reaction of the connective tissue component of the rat left ventricular myocardium to hypertrophy induced by ventral aorta coarctation in the subdiaphragmatic part was studied by electron microscopy with the use of morphometric analysis. The animals were sacrificed 1, 5 and 10 days after the operation. It the heart of intact animals, the relative amount of the connective tissue was equal to 10.2%. Of this number, 2% were cellular elements, 0.2 and 8% were fibrous and amorphous parts of the intermediate tissue, respectively. In the emergency stage of hypertrophy there was an augmentation of the total amount of the connective tissue, the ratio of its diverse components varied with time. Moreover, an activation of the synthetic processes was recorded in the cells of the fibroblastic type.

摘要

运用形态计量学分析的电子显微镜技术,研究了大鼠左心室心肌结缔组织成分对膈下部分腹主动脉缩窄所致肥大的反应。术后1天、5天和10天处死动物。在正常动物心脏中,结缔组织的相对含量为10.2%。其中,2%为细胞成分,0.2%和8%分别为中间组织的纤维和无定形部分。在肥大的急性期,结缔组织总量增加,其不同成分的比例随时间变化。此外,还记录到成纤维细胞类型的细胞中合成过程的激活。

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