Pavillard E R, Miles H
Clin Ther. 1980;3(Spec Issue):134-8.
The minimum inhibitory concentrations (MICs) of cefoperazone for 507 clinical isolates of Pseudomonas aeruginosa were measured by plate dilution technique. On a cumulative percentage basis, 81% of isolates were inhibited by less than or equal 3.13 microgram/ml of cefoperazone. The minimum bactericidal concentration (MBC) was found to be generally twice the MIC. Synergy occurred between cefoperazone and tobramycin, judged by a lowering of the MIC in 69% of isolates, for which the MIC of cefoperazone alone was less than or equal to 6.2 microgram/ml.
采用平板稀释法测定了头孢哌酮对507株铜绿假单胞菌临床分离株的最低抑菌浓度（MIC）。以累积百分比计算，81%的分离株被小于或等于3.13微克/毫升的头孢哌酮所抑制。发现最低杀菌浓度（MBC）通常是MIC的两倍。对于单独使用头孢哌酮的MIC小于或等于6.2微克/毫升的分离株，通过69%的分离株MIC降低判断，头孢哌酮与妥布霉素之间存在协同作用。
