表皮生长因子的促生长活性可被佛波酯中和。
EGF growth promoting activity is neutralized by phorbol esters.
作者信息
Lechner J F, Kaighn M E
出版信息
Cell Biol Int Rep. 1980 Jan;4(1):23-8. doi: 10.1016/0309-1651(80)90005-3.
PMID:6446408
Abstract
The tumor-promoter, TPA, stimulates growth of human epithelial cells but not that of normal fibroblasts. In the presence of either EGF or FGF, TPA antagonizes the growth stimulatory activity of both factors in both cell lines.
摘要
肿瘤促进剂佛波酯（TPA）可刺激人上皮细胞生长，但对正常成纤维细胞无此作用。在表皮生长因子（EGF）或成纤维细胞生长因子（FGF）存在的情况下，TPA可拮抗这两种因子对两种细胞系的生长刺激活性。
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