Bartlett P F, Sim F R, Reade P C, Prime S S
Transplantation. 1978 Mar;25(3):126-30. doi: 10.1097/00007890-197803000-00006.
It was demonstrated in this study that bovine odontogenic tissues and the dissociated cell preparations of such tissues, when transplated to the subcapsular kidney site of hypothymic mice, retained their phenotypic expression and continued function to produce their recognisable products, dentine and enamel matrices. It was also shown that in the grafts of dissociated odontogenic tissues, cell sorting occurred so that histotypical tissues were formed and that their function produced readily recognisable dentine and enamel matrices. Attention has been drawn to the usefulness of this model for studying a variety of events that occur during odontogenesis.
本研究表明，牛牙源性组织及其解离的细胞制剂移植到胸腺发育不全小鼠的肾被膜下部位时，保留了其表型表达并继续发挥功能，产生可识别的产物牙本质和釉质基质。还表明，在解离的牙源性组织移植物中，发生了细胞分选，从而形成了组织学典型的组织，并且其功能产生了易于识别的牙本质和釉质基质。人们已经注意到该模型对于研究牙发生过程中发生的各种事件的有用性。
