Dorn M, Kienitz T, Ryckmanns F
Hautarzt. 1980 Jan;31(1):30-4.
Patients with onychomycosis (tinea) of finger- and toenails underwent combined treatment: avulsion of nail plate, local antimycotic and systemic griseofulvin treatment. Avulsion of the involved nails was performed by the patients themselves chemo-mechanically using 50% KI-ointment. 1,500 nails were successfully removed. Out of 250 patients 101 were clinically and mycologically cured after a median delay of 6.5 months. Only 50% of the 101 patients remained cured up to one year after cessation of therapy. Atraumatic nail avulsion in combination with chemotherapy is a reliable, inexpensive, painless, and effective alternative method to surgical excision treating onychomycosis.
患有手指甲和脚趾甲癣（灰指甲）的患者接受了联合治疗：拔除甲板、局部抗真菌治疗和全身性灰黄霉素治疗。受累指甲由患者本人使用50%碘化钾软膏通过化学机械方法自行拔除。成功拔除了1500个指甲。250名患者中，101名在中位延迟6.5个月后临床和真菌学治愈。在治疗停止后长达一年的时间里，这101名患者中只有50%保持治愈状态。无创性指甲拔除联合化学疗法是一种可靠、廉价、无痛且有效的替代手术切除治疗甲癣的方法。
