Baluch J, Sussman R, Resnick J
Mol Gen Genet. 1980;178(2):317-23. doi: 10.1007/BF00270478.
The requirement for amplified synthesis of recA protein in the UV-promoted induction of coliphage lambda was studied. We confirmed that a low concentration of rifampicin inhibited specifically the increased synthesis of recA protein after an inducing treatment (Satta and Pardee, 1978). Under these conditions, using an optimal dose of UV, E. coli lysogens were induced, producing active phage. The drug delayed the onset of induction and with increasing concentrations affected the yield of phage, but all the cells lysed. The results established that induction can proceed without amplification of recA protein synthesis.
研究了在紫外线促进的大肠杆菌噬菌体λ诱导过程中recA蛋白扩增合成的需求。我们证实，低浓度的利福平特异性抑制诱导处理后recA蛋白合成的增加（萨塔和帕迪，1978年）。在这些条件下，使用最佳剂量的紫外线诱导大肠杆菌溶原菌，产生有活性的噬菌体。该药物延迟了诱导的开始，并且随着浓度增加影响噬菌体产量，但所有细胞都会裂解。结果表明，诱导可以在不扩增recA蛋白合成的情况下进行。
