社会选择对亨廷顿舞蹈症群体动态的影响。
The effect of social selection on the population dynamics of Huntington's disease.
作者信息
Yokoyama S, Templeton A
出版信息
Ann Hum Genet. 1980 May;43(4):413-7. doi: 10.1111/j.1469-1809.1980.tb01574.x.
Abstract
Wallace (1976) postulated the importance of social selection on the frequency of Huntington's disease. This effect of social selection was studied with respect to the population dynamics of Huntington's disease genes. It is shown that social selection operates mainly through heterozygotes. Existing data indicate that the frequency of Huntington's disease in the population is determined by its social effects.
摘要
华莱士（1976年）推测了社会选择对亨廷顿舞蹈症发病率的重要性。针对亨廷顿舞蹈症基因的种群动态对这种社会选择效应进行了研究。结果表明，社会选择主要通过杂合子起作用。现有数据表明，该疾病在人群中的发病率由其社会影响决定。
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