[年龄依赖性免疫参数]
[Age-dependent immunological parameters].
作者信息
Tittor W, Mundinger A, Seelig P
出版信息
Immun Infekt. 1980;8(1):5-10.
PMID:6447663
Abstract
Lymphocyte stimulation, frequency of autoantibodies and concentration of immunoglobuline classes were investigated in 90 persons of 3 age-groups (5--15, 30--40 and 65--95 years of age). An age dependent decrease of MLC- and PhA-reactivity was observed. In contrast, the frequency of autoantibodies and the concentration of IgA increased with age. Individuals with a positive antinuclear factor demonstrated decreased IgA levels. No correlation between lymphocyte stimulation and autoantibody-frequency could be observed.
摘要
对90名3个年龄组（5 - 15岁、30 - 40岁和65 - 95岁）的人员进行了淋巴细胞刺激、自身抗体频率和免疫球蛋白类别浓度的研究。观察到混合淋巴细胞培养（MLC）和植物血凝素（PhA）反应性随年龄下降。相反，自身抗体频率和IgA浓度随年龄增加。抗核因子呈阳性的个体IgA水平降低。未观察到淋巴细胞刺激与自身抗体频率之间的相关性。
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