Lubitz W, Reichert A, Birkmayer G
Acta Neuropathol. 1980;50(3):211-6. doi: 10.1007/BF00688756.
Plasma membrane-enriched fractions were isolated from human gliomas and brain white matter. These membrane fractions were characterized by electron microscopy and by the distribution of the membrane marker enzymes (Na+K+)-ATPase and 2',3'-cyclic AMP-3'-phosphohydrolase. The comparison of the membranes from tumor and control material by SDS gel electrophoresis reveals an altered tumor membrane. Two proteins of a molecular weight of about 70,000 dalton and 30,000 dalton are found to be more expressed in the tumor membrne.
从人脑胶质瘤和脑白质中分离出富含质膜的组分。通过电子显微镜以及膜标记酶（Na + K +）-ATP酶和2'，3'-环磷酸腺苷-3'-磷酸水解酶的分布对这些膜组分进行表征。通过SDS凝胶电泳对肿瘤和对照材料的膜进行比较，发现肿瘤膜发生了改变。发现两种分子量约为70,000道尔顿和30,000道尔顿的蛋白质在肿瘤膜中表达更高。
