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胎鼠对α-亚麻酸的代谢

The metabolism of alpha-linolenic acid by the foetal rat.

作者信息

Sanders T A, Naismith D J

出版信息

Br J Nutr. 1980 Sep;44(2):205-8. doi: 10.1079/bjn19800028.

DOI:10.1079/bjn19800028
PMID:6448628
Abstract

The metabolism of [I-C14]linolenic acid (18:3 omega 3) by the foetal rat was studied in vivo and in vitro It is suggested that foetal brain has the capacity to convert linolenic to docosahexaenoic (22: 6 omega 3) acid to meet its requirements for docosalhexaenoic acid.

摘要

对胎鼠体内和体外的[I-C14]亚麻酸（18:3 ω-3）代谢进行了研究。结果表明，胎脑具有将亚麻酸转化为二十二碳六烯酸（22:6 ω-3）的能力，以满足其对二十二碳六烯酸的需求。

相似文献

1
The metabolism of alpha-linolenic acid by the foetal rat.胎鼠对α-亚麻酸的代谢
Br J Nutr. 1980 Sep;44(2):205-8. doi: 10.1079/bjn19800028.
2
Comparison of the metabolism of linoleic and linolenic acids in the fetal rat.胎鼠体内亚油酸和亚麻酸代谢的比较。
Ann Nutr Metab. 1987;31(6):349-53. doi: 10.1159/000177293.
3
The incorporation of linolenic aid and docosahexaenoic acid into liver and brain lipids of developing rats.亚麻酸和二十二碳六烯酸掺入发育中大鼠的肝脏和脑脂质中。
FEBS Lett. 1972 Oct 1;26(1):127-9. doi: 10.1016/0014-5793(72)80557-x.
4
Relationship between essential fatty acid requirements of aquatic animals and the capacity for bioconversion of linolenic acid to highly unsaturated fatty acids.水生动物必需脂肪酸需求与亚麻酸生物转化为高度不饱和脂肪酸能力之间的关系。
Comp Biochem Physiol B. 1979;63(3):295-8. doi: 10.1016/0305-0491(79)90251-7.
5
Hepatic metabolism of dietary alpha-linolenic acid in suckling rats, and its possible importance in polyunsaturated fatty acid uptake by the brain.哺乳期大鼠膳食中α-亚麻酸的肝脏代谢及其在大脑摄取多不饱和脂肪酸中的潜在重要性。
Ann Nutr Metab. 1986;30(5):316-23. doi: 10.1159/000177209.
6
Incorporatsion of 14C-docosahexaenoic acid into lipids of rats.14C-二十二碳六烯酸掺入大鼠脂质的情况。
Proc Soc Exp Biol Med. 1976 Jul;152(3):298-301. doi: 10.3181/00379727-152-39383.
7
The influence of alpha-linolenic acid (18: 3omega3) on the metabolism of gamma-linolenic acid (18: 3omega6) in the rat.α-亚麻酸（18:3ω3）对大鼠γ-亚麻酸（18:3ω6）代谢的影响。
Br J Nutr. 1977 Jul;38(1):137-40. doi: 10.1079/bjn19770069.
8
Essential fatty acids and fetal brain growth.必需脂肪酸与胎儿大脑发育
Lancet. 1976 Feb 28;1(7957):452-3. doi: 10.1016/s0140-6736(76)91476-8.
9
Formula alpha-linolenic (18:3(n - 3)) and linoleic (18:2(n - 6)) acid influence neonatal piglet liver and brain saturated fatty acids, as well as docosahexaenoic acid (22:6(n - 3)).
Biochim Biophys Acta. 1992 May 8;1125(3):262-7. doi: 10.1016/0005-2760(92)90054-y.
10
[Effect of the streptozotocin diabetes upon the in vivo conversion of [I-14C] gamma-linolenic and dihomo-gamma-linolenic acids into arachidonic acid in rats (author's transl)].链脲佐菌素诱导的糖尿病对大鼠体内[I-14C]γ-亚麻酸和二高-γ-亚麻酸转化为花生四烯酸的影响（作者译）
Diabete Metab. 1979 Mar;5(1):43-6.

引用本文的文献

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Perinatal Dietary Polyunsaturated Fatty Acids in Brain Development, Role in Neurodevelopmental Disorders.围产期多不饱和脂肪酸在大脑发育中的作用及其与神经发育障碍的关系。
Nutrients. 2021 Apr 2;13(4):1185. doi: 10.3390/nu13041185.
2
Polyunsaturated fatty acid deficiency during neurodevelopment in mice models the prodromal state of schizophrenia through epigenetic changes in nuclear receptor genes.在小鼠神经发育过程中缺乏多不饱和脂肪酸会通过核受体基因的表观遗传变化模拟精神分裂症的前驱状态。
Transl Psychiatry. 2017 Sep 5;7(9):e1229. doi: 10.1038/tp.2017.182.
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High Fat Diet Administration during Specific Periods of Pregnancy Alters Maternal Fatty Acid Profiles in the Near-Term Rat.
孕期特定阶段给予高脂饮食会改变近足月大鼠的母体脂肪酸谱。
Nutrients. 2016 Jan 4;8(1):25. doi: 10.3390/nu8010025.