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[转铁蛋白、生长调节素与生长]

[Transferrin, somatomedins and growth].

作者信息

Donnadieu M, Schimpff R M, Garnier P, Martinez M J, Chaussain J L, Job J C

出版信息

C R Seances Soc Biol Fil. 1980;174(4):564-73.

PMID:6449240
Abstract

Plasma transferrin is significantly positively correlated to the growth velocity in normal children and children with various growth disorders. In hypopituitary dwarfs, both plasma transferrin and somatomedin are significantly lower than in controls. Acute variations of the plasma transferrin levels could be involved in the regulation of the GH secretion by a feedback mechanism. Yet, transferrin is neither a somatomedin or a somatomedin-binding protein, and the mechanisms relating growth to transferrin remain unknown.

摘要

血浆转铁蛋白与正常儿童及患有各种生长障碍的儿童的生长速度显著正相关。在垂体功能减退性侏儒症患者中,血浆转铁蛋白和生长调节素均显著低于对照组。血浆转铁蛋白水平的急性变化可能通过反馈机制参与生长激素分泌的调节。然而,转铁蛋白既不是生长调节素,也不是生长调节素结合蛋白,生长与转铁蛋白之间的关系机制仍不清楚。

相似文献

1
[Transferrin, somatomedins and growth].[转铁蛋白、生长调节素与生长]
C R Seances Soc Biol Fil. 1980;174(4):564-73.
2
[Somatomedin, transferrin and growth regulation in children].[儿童中的生长调节素、转铁蛋白与生长调节]
Pathol Biol (Paris). 1980 Jun;28(6):373-4.
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Horm Metab Res. 1984 Oct;16(10):539-43. doi: 10.1055/s-2007-1014844.
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Arch Fr Pediatr. 1980 Oct;37(8):515-9.
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[Behavior of the somatotropic hormone and of somatomedin (sulfation factor) in achondroplasia].[生长激素及生长调节素(硫酸化因子)在软骨发育不全中的表现]
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[Somatomedin following administration of growth hormone in pituitary dwarfism].[垂体性侏儒症患者注射生长激素后的生长介素]
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A possible relationship between serum transferrin, growth hormone secretion and height velocity in children.儿童血清转铁蛋白、生长激素分泌与身高增长速度之间的可能关系。
Acta Endocrinol (Copenh). 1980 Feb;93(2):134-8. doi: 10.1530/acta.0.0930134.
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[Somatomedins and growth disorders].[生长调节素与生长紊乱]
Rev Prat. 1979 Feb 21;29(11):925-6, 929-30, 933-4.