Donnadieu M, Schimpff R M, Garnier P, Martinez M J, Chaussain J L, Job J C
C R Seances Soc Biol Fil. 1980;174(4):564-73.
Plasma transferrin is significantly positively correlated to the growth velocity in normal children and children with various growth disorders. In hypopituitary dwarfs, both plasma transferrin and somatomedin are significantly lower than in controls. Acute variations of the plasma transferrin levels could be involved in the regulation of the GH secretion by a feedback mechanism. Yet, transferrin is neither a somatomedin or a somatomedin-binding protein, and the mechanisms relating growth to transferrin remain unknown.
血浆转铁蛋白与正常儿童及患有各种生长障碍的儿童的生长速度显著正相关。在垂体功能减退性侏儒症患者中,血浆转铁蛋白和生长调节素均显著低于对照组。血浆转铁蛋白水平的急性变化可能通过反馈机制参与生长激素分泌的调节。然而,转铁蛋白既不是生长调节素,也不是生长调节素结合蛋白,生长与转铁蛋白之间的关系机制仍不清楚。