Koller L D, Roan J G
J Environ Pathol Toxicol. 1980 Aug;4(1):393-8.
Mice were exposed to various dosages of lead, cadmium, or methylmercury for 10 weeks. At the end of the feeding trial, splenic lymphocytes were evaluated for responsiveness in mixed lymphocyte cultures. Cadmium and methylmercury as well as one dose level of lead tended (not significant) to stimulate the lymphocyte reaction. These results are discussed and compared to other investigations concerned with the effect these environmental contaminants have on the cell mediated immune response of animals.
将小鼠暴露于不同剂量的铅、镉或甲基汞中10周。在喂养试验结束时，评估脾淋巴细胞在混合淋巴细胞培养中的反应性。镉、甲基汞以及一个剂量水平的铅倾向于（不显著）刺激淋巴细胞反应。对这些结果进行了讨论，并与其他有关这些环境污染物对动物细胞介导免疫反应影响的研究进行了比较。
