Borutta A, Heinrich R, Senkel H
Zahn Mund Kieferheilkd Zentralbl. 1980;68(4):322-6.
A double blind experiment made twice for two weeks was used to determine the effectiveness of chlorhexidine-containing preparations (0.2% solution, 1% gel) from the oral hygiene index, the sulcal bleeding index, and the rate of flow of sulcal fluid, with a total of 64 schoolchildren serving as subjects. The results of a longitudinal comparison confirmed the plaque-inhibiting effect of the chemotherapeutic agent, whereas inflammations of the gingiva were seen to be essentially unaffected. Short-time application of chlorhexidine is recommended as a supportive measure of oral hygiene to be taken in specific cases of indication.
通过一项为期两周、进行了两次的双盲实验，根据口腔卫生指数、龈沟出血指数和龈沟液流速来确定含氯己定制剂（0.2%溶液、1%凝胶）的有效性，共有64名学童作为受试者。纵向比较的结果证实了该化疗药物的抑制牙菌斑作用，而牙龈炎症基本未受影响。建议在特定适应症情况下，短期应用氯己定作为口腔卫生的辅助措施。
