Gründemann L J M M, Timmerman M F, van der Velden U, van der Weijden G A
Afdeling Parodontologie van het Academisch Centrum Tandheelkunde Amsterdam (ACTA).
Ned Tijdschr Tandheelkd. 2002 Jul;109(7):255-9.
Aim of the present study was to investigate whether the use of an oxidising mouthrinse as an adjunct to chlorhexidine is efficacious in reducing stain, plaque and gingivitis. This study had a single-blind, 2-group parallel design, including a 14-day experimental non-brushing period during which 1 group (n = 14) used chlorhexidine alone (CHX) and the other (n = 14) used chlorhexidine in combination with an oxidising agent. Patients were randomly assigned to either group. The gingival condition was evaluated at baseline by means of bleeding on marginal probing. The examination after 14 days of rinsing included the evaluation of plaque, bleeding on marginal probing and stain (GMSI: gingival modification of the stain index). The results showed at day 14 a significant difference between the 2 groups for plaque and gingival bleeding. The proportion of stained surfaces was less in the CHX + PER-group (28%), than in the chlorhexidine group. The adjunctive use of an oxidising agent peroxyborate to chlorhexidine, proved to be superior to chlorhexidine alone with regard to the inhibition of plaque and development of gingivitis.
本研究的目的是调查使用氧化漱口水作为氯己定的辅助手段在减少色斑、牙菌斑和牙龈炎方面是否有效。本研究采用单盲、两组平行设计，包括一个为期14天的非刷牙实验期，在此期间，一组（n = 14）仅使用氯己定（CHX），另一组（n = 14）使用氯己定与一种氧化剂联合使用。患者被随机分配到两组中的任意一组。在基线时通过龈沟探诊出血来评估牙龈状况。冲洗14天后的检查包括对牙菌斑、龈沟探诊出血和色斑（GMSI：色斑指数的牙龈修正值）的评估。结果显示，在第14天时，两组在牙菌斑和牙龈出血方面存在显著差异。CHX + PER组的染色表面比例（28%）低于氯己定组。在抑制牙菌斑和牙龈炎发展方面，向氯己定中添加氧化剂过硼酸盐被证明优于单独使用氯己定。
