Brieler H S, Thiede A
J Cardiovasc Surg (Torino). 1980 Sep-Oct;21(5):590-5.
Pseudo-endothelial cell growth on Sparks' auto-alloplastic vascular prostheses which had been grafted in the arterial circulatory system are examined by light- and electron microscopy at different intervals after application. The obtained data clarify that in future we should speak of prosthetic endothelium or lining cells when referring to those cells which line the inner surface of prostheses; the present study reveals that these cells lack some important criteria, e.g. complete basement membrane and intercellular bridges, by which real endothelial cells are distinguished. The rapid and complete growth of lining cells, expected to accompany use of Sparks' prostheses, could not be confirmed by the present experiments. Using a new microsurgical experimental model in the rat, we were able to show that even in a small animal species prosthetic arterial replacement is possible. Hereby, an important contribution has been made to microsurgical work in the field of experimental vascular surgery with a technique hitherto unknown in the literature.
对移植于动脉循环系统的斯帕克斯自体同种异体血管假体上的假性内皮细胞生长情况，在植入后的不同时间段通过光学显微镜和电子显微镜进行检查。所获数据表明，今后在提及假体内表面的细胞时，我们应称之为假体内皮或衬里细胞；本研究显示，这些细胞缺乏一些区分真正内皮细胞的重要标准，例如完整的基底膜和细胞间桥。目前的实验无法证实预期会伴随斯帕克斯假体使用的衬里细胞的快速且完全生长。通过在大鼠身上使用一种新的显微外科实验模型，我们能够证明即使在小型动物物种中，假体动脉置换也是可行的。据此，我们用一种文献中迄今未知的技术，为实验血管外科领域的显微外科工作做出了重要贡献。
