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[聚对苯二甲酸乙二酯(涤纶)人工血管作为动脉替代物。商用移植体作为犬腹主动脉替代物的价值(作者译)]

[Polyethylene terephtalate (Dacron) prostheses as arterial substitutes. Value of commercial grafts as abdominal aorta substitutes in the dog (author's transl)].

作者信息

Guidoin R, Levaillant P A, Marois M, Gosselin C, Martin L, Rouleau C, Garneau P, Noel H P, Blais P

出版信息

J Mal Vasc. 1980;5(1):3-12.

PMID:6450812
Abstract

Most of the presently available Dacron fabric grafts are either woven or knitted; some are velours. Whereas the various configurations and textures can be easily recognized and classified with respect to morphology, structure, porosity and fabric tenacity, it is also necessary to establish their post-implantation healing characteristics. Canine models have been used to investigate the healing characteristics of 18 types of prostheses over implantation periods from one to six months using techniques of scanning electron microscopy and conventional light microscopy. Velours exhibit superiar tissue ingrowth but the internal tissue lining does seldom embeds all of the fibres. Complete neoendothelialization is not achieved; the process appears more closely linked to haemodynamic factors such as shear forces acting postfacto on blood deposits as opposed to graft porosity facilitating ingrowth. More meaningful criteria of performance must be found to allow a closer matching between the available products and the individual clinical needs of each situation.

摘要

目前市面上大多数涤纶织物移植物要么是编织的,要么是针织的;有些是绒面的。虽然各种形态、结构、孔隙率和织物韧性的配置和质地很容易识别和分类,但确定它们植入后的愈合特性也很有必要。犬类模型已被用于通过扫描电子显微镜和传统光学显微镜技术,研究18种植入物在1至6个月植入期内的愈合特性。绒面移植物表现出优异的组织向内生长,但内部组织衬里很少能包埋所有纤维。不能实现完全的新内膜化;这个过程似乎与血流动力学因素,如作用于血栓的剪切力等关系更为密切,而不是与促进向内生长的移植物孔隙率相关。必须找到更有意义的性能标准,以便使现有产品与每种情况的个体临床需求更紧密匹配。

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