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沙眼衣原体与因输卵管成形术而入选的女性腹部标本中的慢性炎症相关。

Chlamydia trachomatis associated with chronic inflammation in abdominal specimens from women selected for tuboplasty.

作者信息

Henry-Suchet J, Catalan F, Loffredo V, Sanson M J, Debache C, Pigeau F, Coppin R

出版信息

Fertil Steril. 1981 Nov;36(5):599-605. doi: 10.1016/s0015-0282(16)45857-7.

Abstract

Chronic inflammation is a frequent cause of tuboplasty failure. Therefore, it would be useful for one to know the microbiologic agent of infection and to treat it before the tuboplasty. By laparoscopy, a search for Chlamydia trachomatis, Ureaplasma urealyticum, and other microbiologic agents was carried out in the peritoneum and tubes of 118 women divided into 3 groups. Sixty-nine had a checkup before tuboplasty, of which 30 were found to have a chronic inflammatory condition discovered during laparoscopy (group 1) and 39 to have no sign of inflammation (group 2). Forty-nine women with a completely normal pelvis, being followed for possible sterility, were used as a control group. Cultures and serodiagnosis show a significant difference for C. trachomatis between the pathologic groups and the control group. They show no noticeable difference for U. urealyticum. These findings, compared with those by other authors, indicate that C. trachomatis could be an important microbiologic agent in tubal sterility, strongly connected with a low-grade chronic inflammatory condition, and their presence at the time of tuboplasty is to be considered.

摘要

慢性炎症是输卵管成形术失败的常见原因。因此,在进行输卵管成形术前了解感染的微生物病原体并进行治疗是很有必要的。通过腹腔镜检查,对118名女性的腹膜和输卵管进行了沙眼衣原体、解脲脲原体及其他微生物病原体的检测,这些女性被分为3组。69名女性在输卵管成形术前接受了检查,其中30名在腹腔镜检查中发现患有慢性炎症(第1组),39名没有炎症迹象(第2组)。49名骨盆完全正常但因可能不孕而接受随访的女性作为对照组。培养和血清学诊断显示,病理组与对照组之间沙眼衣原体存在显著差异。解脲脲原体则无明显差异。与其他作者的研究结果相比,这些发现表明沙眼衣原体可能是输卵管性不孕的一种重要微生物病原体,与低度慢性炎症密切相关,在输卵管成形术时应考虑其存在。

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