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[女性生殖道衣原体感染与输卵管性不孕的关系]

[Relationship between chlamydial infection in female genital tract and tubal infertility].

作者信息

Li Y, Luo L

机构信息

Tongji Hospital of Tongji Medical University, Wuhan.

出版信息

Zhonghua Fu Chan Ke Za Zhi. 1995 Aug;30(8):471-4.

PMID:8565694
Abstract

OBJECTIVE

To detect the incidence of chlamydial infection in female genital tract and it's relationship with tubal infertility.

METHODS

Fourty-eight infertile women underwent laparoscopies were divided into study group (n = 32) and control group (n = 16). Samples were taken from the upper genital tract (including endometrium, tubal fimbriae, peritoneal fluid and pelvic adhesion) and lower genital tract (cervix). The monoclonal direct immunofluorescent method was used to assay chlamydia trachomatis the results of these two groups were compared.

RESULTS

The positive percentage of cervical clamydial infections between the two groups were not significant lydifferent (P > 0.05). But there showed a significant difference between the two groups if compared by the incidence of the whole genital tract 32.5% and 10.2% (P < 0.01). The tubal positive percentage is 66.7% in the study group. Which is the highest among other locations such as cervix, endometrium, etc (P < 0.05).

CONCLUSION

This study indicates that fallopian tube is a high prevalent site of chlamydial infection, and chlamydial infection in female genital tract is a principal pathogenic factor of tubal infertility. Early laparoscopy for tubal infertility and chlamydia trachomatis sampling is the key method for early diagnosis and treatment of chlamydia trachomatis.

摘要

目的

检测女性生殖道衣原体感染的发生率及其与输卵管性不孕的关系。

方法

将48例行腹腔镜检查的不孕女性分为研究组(n = 32)和对照组(n = 16)。从女性上生殖道(包括子宫内膜、输卵管伞端、腹腔液和盆腔粘连组织)及下生殖道(宫颈)采集样本。采用单克隆直接免疫荧光法检测沙眼衣原体,比较两组检测结果。

结果

两组宫颈衣原体感染阳性率差异无统计学意义(P > 0.05)。但比较整个生殖道衣原体感染发生率时,两组差异有统计学意义,分别为32.5%和10.2%(P < 0.01)。研究组输卵管衣原体感染阳性率为66.7%,在宫颈、子宫内膜等其他部位中最高(P < 0.05)。

结论

本研究表明,输卵管是衣原体感染的高发部位,女性生殖道衣原体感染是输卵管性不孕的主要致病因素。对输卵管性不孕患者早期行腹腔镜检查及沙眼衣原体采样是早期诊断和治疗沙眼衣原体感染的关键方法。

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1
[Relationship between chlamydial infection in female genital tract and tubal infertility].[女性生殖道衣原体感染与输卵管性不孕的关系]
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2
[The relationship between female infertility and genital inflammation of Chlamydia trachomatis].[女性不孕与沙眼衣原体生殖道炎症的关系]
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Eur J Epidemiol. 1992 Sep;8(5):645-9. doi: 10.1007/BF00145378.
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Tubal infertility: serologic relationship to past chlamydial and gonococcal infection. World Health Organization Task Force on the Prevention and Management of Infertility.输卵管性不孕:与既往衣原体和淋球菌感染的血清学关系。世界卫生组织不孕症预防和管理特别工作组。
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J Gynecol Obstet Biol Reprod (Paris). 1989;18(2):167-72.
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Chlamydial serology in women with tubal infertility.输卵管性不孕女性的衣原体血清学
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