Hartmann R, Ratzmann G W, Seer O T, Zöllner H
Z Gesamte Inn Med. 1978 Feb 15;33(4):122-5.
Intravenous application of 1 mg glucagon causes a significant decrease of the magnesium, calcium, and phosphate concentrations in the serum. Concerning the potassium level there is a biphasic change of concentration. Initially a significant increase of the potassium concentration is to be measured which transgresses into a longer phase of decrease of concentration. The possible causes of these changes of electrolytes after application of glucagon are discussed and it is referred to the possible clinical importance. In longer therapeutic application of glucagon a control of the serum parameters of the electrolytes metabolism appears indicated.
静脉注射1毫克胰高血糖素会导致血清中镁、钙和磷酸盐浓度显著降低。关于钾水平,浓度有双相变化。最初可测得钾浓度显著升高,随后进入较长的浓度降低阶段。文中讨论了应用胰高血糖素后电解质发生这些变化的可能原因,并提及了可能的临床重要性。在长期应用胰高血糖素进行治疗时,似乎有必要对电解质代谢的血清参数进行监测。