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通过在细胞凝胶上进行等电聚焦在波兰人群中可检测到的磷酸葡萄糖变位酶-1(PGM1)位点的亚型。

Subtypes of the phosphoglucomutase-1 (PGM1) locus detectable in Polish populations by isoelectric focusing on cellogel.

作者信息

Dobosz T, Kozioł P

出版信息

Hum Genet. 1980;56(1):119-21. doi: 10.1007/BF00281581.

Abstract

The technique of isoelectric focusing on methylated 'cellogel' strips (CAGIF) was used to confirm the presence of four alleles of PGM1 in human red cell lysates. The subtypes of PGM1 were determined in two Polish population samples, from Southwestern Poland (Wrocław region, n=321) and Southeastern Poland (Lubin region, n=212). Ten different phenotypes are considered as gene products of four alleles at PGM1, with the following frequencies: Wrocław: PGM1F, 0.1044; PGM1S, 0.5966; PGM2F, 0.0685; and PGM2S, 0.2305; Lublin: PGM1F, 0.1439; PGM1S, 0.6014; PGM2F, 0.0825; and PGM2S, 0.1722.

摘要

采用在甲基化“细胞凝胶”条上进行等电聚焦的技术(CAGIF)来确认人类红细胞裂解物中PGM1的四个等位基因的存在。在来自波兰西南部(弗罗茨瓦夫地区,n = 321)和波兰东南部(卢宾地区,n = 212)的两个波兰人群样本中确定了PGM1的亚型。十种不同的表型被认为是PGM1四个等位基因的基因产物,其频率如下:弗罗茨瓦夫:PGM1F,0.1044;PGM1S,0.5966;PGM2F,0.0685;PGM2S,0.2305;卢宾:PGM1F,0.1439;PGM1S,0.6014;PGM2F,0.0825;PGM2S,0.1722。

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