哌拉西林在肾衰竭患者中的药代动力学
Pharmacokinetics of piperacillin in renal failure.
作者信息
George C R, Burgoyne J, Funnell G R, Robinson P, Collignon P, Meads K, Guinness M D
出版信息
Med J Aust. 1981 Jan 10;1(1):35-6. doi: 10.5694/j.1326-5377.1981.tb135286.x.
Abstract
Patients with chronic renal failure who received bolus doses of piperacillin maintained high serum levels for up to six hours. The percentage of the injected dose which was detectable in the urine in 24 hours was reduced proportionately to the severity of the renal failure.
摘要
接受大剂量哌拉西林治疗的慢性肾衰竭患者血清高水平维持长达6小时。24小时尿液中可检测到的注射剂量百分比与肾衰竭的严重程度成比例降低。
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