生物活性DNA中的碱不稳定位点：辐射诱导的潜在断裂与脱嘌呤位点的比较
Alkali-labile sites in biologically active DNA: comparison of radiation induced potential breaks and apurinic sites.
作者信息
Lafleur M V, Woldhuis J, Loman H
出版信息
Int J Radiat Biol Relat Stud Phys Chem Med. 1981 Feb;39(2):113-8. doi: 10.1080/09553008114550131.
PMID:6453101
Abstract
Gamma-ray induced alkali-labile sites, which are converted into breaks by alkali or heat, are compared with apurinic sites in both single-stranded and phi X174RF-DNA. It is shown that the kinetics of the conversion into breaks are completely different for both sites. The conclusion is: the gamma-ray induced alkali-labile sites are not identical with apurinic or/and apyrimidinic sites.
摘要
将γ射线诱导产生的碱不稳定位点（经碱或加热后会转变为断裂处）与单链DNA和φX174RF-DNA中的脱嘌呤位点进行了比较。结果表明，这两种位点转变为断裂处的动力学完全不同。结论是：γ射线诱导产生的碱不稳定位点与脱嘌呤或/和脱嘧啶位点并不相同。
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