静脉给药后胆汁和胆囊壁中的头孢哌酮浓度。
Cefoperazone concentrations in bile and gall bladder wall after intravenous administration.
作者信息
Nakamura T, Hashimoto I, Sawada Y, Mikami J, Bekki E, Hirasawa S, Abe H, Watanabe Y
出版信息
Antimicrob Agents Chemother. 1980 Dec;18(6):980-2. doi: 10.1128/AAC.18.6.980.
Abstract
Cefoperazone concentrations in the common duct bile, gall bladder bile, and gall bladder wall were determined in four patients with cholelithiasis and one patient with carcinoma of the head of the pancreas, all of whom had normal renal functions. Within 65 min after a 1-g intravenous administration, maximum concentrations ranged from 373.4 to 3,100 micrograms/ml in common duct bile and from 6.8 to 680 micrograms/ml in gall bladder bile. Cefoperazone concentrations per gram of the gall bladder wall ranged from 16.8 to 48.0 micrograms.
摘要
对4例胆石症患者和1例胰头癌患者（所有患者肾功能均正常）测定了胆总管胆汁、胆囊胆汁及胆囊壁中的头孢哌酮浓度。静脉注射1g后65分钟内，胆总管胆汁中的最高浓度范围为373.4至3100微克/毫升，胆囊胆汁中的最高浓度范围为6.8至680微克/毫升。每克胆囊壁中的头孢哌酮浓度范围为16.8至48.0微克。
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