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A possible explanation for the occurrence of increased beta-hexosaminidase activity in pregnancy serum.

作者信息

Hultberg B, Isaksson A

出版信息

Clin Chim Acta. 1981 Jun 18;113(2):135-40. doi: 10.1016/0009-8981(81)90147-9.

DOI:10.1016/0009-8981(81)90147-9
PMID:6454514
Abstract

The activities of the lysosomal enzymes beta-hexosaminidase, beta-glucuronidase, and beta-galactosidase were confirmed to be elevated in serum from pregnant women. The increased activity of beta-hexosaminidase and beta-glucuronidase showed the same changes in the isoenzyme pattern as found in serum from patients with some liver affections. In the light of recent findings, the increased activity of beta-hexosaminidase (and some other lysosomal enzymes) in pregnancy and liver disease might depend upon the non-parenchymal liver cells not being able properly to clear these enzymes from the blood.

摘要

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