肝脏疾病、酒精中毒及妊娠时血清β-N-乙酰氨基己糖苷酶同工酶谱
Isoenzyme pattern of serum beta-hexosaminidase in liver disease, alcohol intoxication, and pregnancy.
作者信息
Hultberg B, Isaksson A
出版信息
Enzyme. 1983;30(3):166-71. doi: 10.1159/000469570.
PMID:6226520
Abstract
The isoenzyme distribution of serum beta-hexosaminidase was studied in 11 pregnant women, 18 patients with cirrhosis of the liver, 14 patients with cholestasis, and 9 chronic alcoholics with acute ethanol intoxication. Serum beta-hexosaminidase activity was elevated in sera from all groups. The results of isoenzyme separation by isoelectric focusing demonstrated that the isoenzyme pattern in the different patient groups was similar to pregnancy with a preferential increase of isoenzyme forms with pI's between 5.6 and 6.8.
摘要
对11名孕妇、18名肝硬化患者、14名胆汁淤积患者和9名急性乙醇中毒的慢性酗酒者的血清β-己糖胺酶同工酶分布进行了研究。所有组血清中的β-己糖胺酶活性均升高。通过等电聚焦分离同工酶的结果表明，不同患者组的同工酶模式与妊娠相似，pI在5.6至6.8之间的同工酶形式优先增加。
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