Localisation of immunoglobulin (IgG) in granulated metrial gland cells of deciduomata of the pseudopregnant rat.

Using an immunoperoxidase technique, after fixation in saturated alcoholic mercuric chloride, it was possible to detect cytoplasmic immunoglobulin (IgG) in granulated metrial gland cells from deciduomata of pseudopregnancy in the rat. The extent of the reaction for IgG was variable but did not appear to be related to the day of pseudopregnancy or to the extent of the decidual reaction. Examination of single cell suspension enabled quantification of IgG-containing cells, but no significant differences were detected in the numbers of positive cells at the days of pseudopregnancy which were examined. Surface IgG was detected on a small proportion of the cells, and they were distinguished from the Fcgamma receptor-bearing cells in the metrial gland of deciduomata of pseudopregnancy.