El-Minawi M F, Wahbi O, El-Bagouri I S, Sharawi M, El-Mallah S Y
J Reprod Med. 1981 Jul;26(7):338-46.
The aim of this work was to study the cardiovascular effects, the acid-base balance in serum electrolytes and chlorides in 50 patients during diagnostic laparoscopy, comparing the use of CO2 and N2O for pneumoperitoneum. The CO2 group showed a significant decrease in pH, a significant increase in pCO2 and a significant decrease in pO2, while the changes in HCO3 and base change were insignificant. In the N2O group, the changes in pH, pCO2, pO2, HCO 3 and base excess were statistically insignificant. The heart rate during CO2 and N2O pneumoperitoneum revealed that both groups showed a significant increase, but in the recovery stage there was a significant increase in the CO2 group (p less than 0.025) and insignificant increase in the N2O group (p greater than 0.05). The other circulatory and electrocardiographic changes are described. CO2 pneumoperitoneum induced a significant decrease in serum chlorides but an insignificant increase in Na and an insignificant decrease in potassium, while the N2O pneumoperitoneum group did not show any significant change in serum electrolytes.
这项研究的目的是在50例患者进行诊断性腹腔镜检查期间，研究使用二氧化碳（CO2）和一氧化二氮（N2O）建立气腹时对心血管系统的影响、血清电解质和氯化物的酸碱平衡。CO2组的pH值显著降低，pCO2显著升高，pO2显著降低，而HCO3和碱剩余的变化不显著。在N2O组中，pH、pCO2、pO2、HCO3和碱剩余的变化无统计学意义。CO2和N2O气腹期间的心率显示，两组均显著增加，但在恢复阶段，CO2组显著增加（p<0.025），N2O组增加不显著（p>0.05）。还描述了其他循环系统和心电图变化。CO2气腹导致血清氯化物显著降低，但钠轻度升高，钾轻度降低，而N2O气腹组血清电解质未显示任何显著变化。
