Garcia e Silva L
Med Cutan Ibero Lat Am. 1980;8(4-6):125-8.
One case of seborrhoeic keratosis with extensive acantholysis and moderate dyskeratosis is reported. The histological features ressembled those of Darier and Hailey-Hailey diseases. Another seborrhoeic wart simultaneously removed had no microscopic abnormalities. The dermatoses in which focal acantholytic dyskeratosis has been observed are reviewed and similarities and possible relationships to epidermolytic hyperkeratosis are discussed. The relative lack of specificity of these changes is emphasised as well as the occasional coexistence of both types and the variability of histological patterns observed on Grover's transient acantholytic dermatosis. These facts suggest a close relationship between the above mentioned histopathological patterns concerning the mechanisms of its production.
报告了1例伴有广泛棘层松解和中度角化不良的脂溢性角化病。其组织学特征与毛囊角化病和黑棘皮病相似。同时切除的另一个脂溢性疣无微观异常。对观察到局灶性棘层松解性角化不良的皮肤病进行了综述,并讨论了其与表皮松解性角化过度的相似性及可能的关系。强调了这些改变相对缺乏特异性,以及两种类型偶尔并存和在格罗弗一过性棘层松解性皮肤病中观察到的组织学模式的变异性。这些事实表明上述组织病理学模式在其产生机制方面关系密切。