Buchanan G R, Glader B E
Am J Dis Child. 1978 Apr;132(4):396-8. doi: 10.1001/archpedi.1978.02120290068013.
Total and differential WBC counts were measured in 88 children with sickle cell hemoglobinopathies during the steady state, vaso-occlusive crisis, and bacterial infection. Steady state leukocyte values were lower than anticipated on the basis of currently available information. Total and segmented leukocyte numbers were greatly increased during vaso-occlusive crisis and infection, but only with bacterial infection was there a consistent increase in bands or nonsegmented leukocytes (mean, 4,580/microliter). On the basis of these data we believe that total and differential leukocyte counts are of value for identifying those children with potentially serious bacterial infections.
在88例镰状细胞血红蛋白病患儿的病情稳定期、血管闭塞性危象期及细菌感染期，检测了白细胞总数及分类计数。病情稳定期的白细胞值低于根据现有信息预期的数值。在血管闭塞性危象期和感染期，白细胞总数及分叶核白细胞数量大幅增加，但仅在细菌感染时，杆状核或未分叶白细胞才有持续增加（平均为4,580/微升）。基于这些数据，我们认为白细胞总数及分类计数对于识别那些可能患有严重细菌感染的儿童具有重要价值。
