Hepburn B
J Rheumatol. 1981 Jul-Aug;8(4):635-8.
A patient with antibodies to RNP, n-DNA, Sm and PM-I is described. The first clinical manifestations of connective tissue disease appeared at age 10. A cystic pulmonary lesion, pericardial effusion and nephropathy appeared after 7 years of disease limited to skin and joints. Pulmonary, pericardial and renal disease all appeared to respond to corticosteroid therapy.
本文描述了一名患有抗核糖核蛋白（RNP）、天然DNA（n-DNA）、史密斯（Sm）和PM-1抗体的患者。结缔组织病的最初临床表现出现在10岁时。在疾病局限于皮肤和关节7年后，出现了肺部囊性病变、心包积液和肾病。肺部、心包和肾脏疾病似乎均对皮质类固醇治疗有反应。
