高滴度抗RNP抗体患者的临床特征及病程
Clinical characteristics and course in patients with high titer anti-RNP antibodies.
作者信息
Lemmer J P, Curry N H, Mallory J H, Waller M V
出版信息
J Rheumatol. 1982 Jul-Aug;9(4):536-42.
PMID:6982334
Abstract
Forty-four patients with high titers of anti-RNP antibodies, without anti-Sm or anti-nDNA antibodies, were studied retrospectively for clinical symptomatology, morbidity and mortality. Seven had died. Eleven had renal disease. Of patients with disease course greater than 7 years, only half had features of overlapping connective tissue diseases. The finding of high titer anti-RNP antibodies without anti-Sm or anti-nDNA did not appear to imply a distinct or unique clinical diagnosis or prognosis.
摘要
对44例抗RNP抗体效价高、无抗Sm或抗nDNA抗体的患者进行回顾性研究，分析其临床症状、发病率和死亡率。7例患者已死亡。11例患者患有肾脏疾病。病程超过7年的患者中，只有一半具有重叠性结缔组织病的特征。抗RNP抗体效价高但无抗Sm或抗nDNA抗体这一发现似乎并不意味着有明确或独特的临床诊断或预后。
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