Falter E W, Hellerer O, Aigner R, Brückner W L
Langenbecks Arch Chir. 1982;356(1):77-81. doi: 10.1007/BF01270606.
The effect of thyrocalcitonin on secondary bone healing was studied in 180 Sprague-Dawley-rats. The right tibia of all the rats was osteotomized. Half of the animals was treated with thyrocalcitonin. Until the 60th postoperative day, the increase in 99mTc-methylendiphosphonate activity was measured and significant differences in ratios were noted. Between the postoperative days 10 to 25, there was a significant difference in the impulse quotients between the thyrocalcitonin and untreated rats (P less than 0.05). These results indicate that thyrocalcitonin may aid in secondary bone healing.
在180只斯普拉格-道利大鼠中研究了降钙素对二期骨愈合的影响。所有大鼠的右胫骨均被截断。一半动物接受降钙素治疗。直到术后第60天，测量了99mTc-亚甲基二膦酸盐活性的增加，并注意到比率上的显著差异。在术后第10至25天之间，降钙素治疗组和未治疗组大鼠的脉冲商数存在显著差异（P小于0.05）。这些结果表明，降钙素可能有助于二期骨愈合。
