哌拉西林与青霉素G治疗淋菌性尿道炎的疗效比较
Comparative efficacy of piperacillin and penicillin G in treatment of gonococcal urethritis.
作者信息
Landis S J, Ramphal R, Mansheim B J, Rand K H, Shands J W
出版信息
Antimicrob Agents Chemother. 1981 Nov;20(5):693-5. doi: 10.1128/AAC.20.5.693.
Abstract
The comparative efficacy of 2 g of piperacillin and 4.8 X 10(6) U of penicillin G in the treatment of uncomplicated gonococcal urethritis was assessed in a randomized prospective study. Sixty-five evaluable patients received piperacillin, and 55 received penicillin G. All patients received either therapy were cured of gonorrhea. We conclude that piperacillin is as efficacious as aqueous procaine penicillin G in the therapy of uncomplicated gonococcal urethritis.
摘要
在一项随机前瞻性研究中，评估了2克哌拉西林和480万单位青霉素G治疗单纯性淋菌性尿道炎的相对疗效。65例可评估患者接受了哌拉西林治疗，55例接受了青霉素G治疗。接受这两种治疗的所有患者的淋病均被治愈。我们得出结论，在治疗单纯性淋菌性尿道炎方面，哌拉西林与普鲁卡因青霉素G水剂疗效相当。
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本文引用的文献
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Piperacillin therapy for serious bacterial infections.
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Piperacillin: human pharmacokinetics after intravenous and intramuscular administration.哌拉西林：静脉注射和肌肉注射后的人体药代动力学
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In vitro antimicrobial activity of piperacillin and seven other beta-lactam antibiotics against Neisseria gonorrhoeae and Haemophilus influenzae, including beta-lactamase producing strains.哌拉西林及其他七种β-内酰胺类抗生素对淋病奈瑟菌和流感嗜血杆菌（包括产β-内酰胺酶菌株）的体外抗菌活性。
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