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哌拉西林与青霉素G治疗淋菌性尿道炎的疗效比较

Comparative efficacy of piperacillin and penicillin G in treatment of gonococcal urethritis.

作者信息

Landis S J, Ramphal R, Mansheim B J, Rand K H, Shands J W

出版信息

Antimicrob Agents Chemother. 1981 Nov;20(5):693-5. doi: 10.1128/AAC.20.5.693.

DOI:10.1128/AAC.20.5.693
PMID:6459764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC181777/
Abstract

The comparative efficacy of 2 g of piperacillin and 4.8 X 10(6) U of penicillin G in the treatment of uncomplicated gonococcal urethritis was assessed in a randomized prospective study. Sixty-five evaluable patients received piperacillin, and 55 received penicillin G. All patients received either therapy were cured of gonorrhea. We conclude that piperacillin is as efficacious as aqueous procaine penicillin G in the therapy of uncomplicated gonococcal urethritis.

摘要

在一项随机前瞻性研究中,评估了2克哌拉西林和480万单位青霉素G治疗单纯性淋菌性尿道炎的相对疗效。65例可评估患者接受了哌拉西林治疗,55例接受了青霉素G治疗。接受这两种治疗的所有患者的淋病均被治愈。我们得出结论,在治疗单纯性淋菌性尿道炎方面,哌拉西林与普鲁卡因青霉素G水剂疗效相当。

相似文献

1
Comparative efficacy of piperacillin and penicillin G in treatment of gonococcal urethritis.哌拉西林与青霉素G治疗淋菌性尿道炎的疗效比较
Antimicrob Agents Chemother. 1981 Nov;20(5):693-5. doi: 10.1128/AAC.20.5.693.
2
Comparison of piperacillin and penicillin in the treatment of uncomplicated gonorrhea.哌拉西林与青霉素治疗单纯性淋病的比较。
Antimicrob Agents Chemother. 1982 May;21(5):727-9. doi: 10.1128/AAC.21.5.727.
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Cefoxitin vs. penicillin in the treatment of uncomplicated gonorrhea.头孢西丁与青霉素治疗单纯性淋病的对比研究
Sex Transm Dis. 1983 Apr-Jun;10(2):53-5. doi: 10.1097/00007435-198304000-00001.
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Penicillin and spectinomycin in treatment of gonococcal urethritis.青霉素与壮观霉素治疗淋菌性尿道炎
Sex Transm Dis. 1982 Jul-Sep;9(3):135-7. doi: 10.1097/00007435-198207000-00007.
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Single-dose treatment of uncomplicated gonococcal urethritis: a comparison of cefonicid and penicillin.
Sex Transm Dis. 1982 Apr-Jun;9(2):93-5. doi: 10.1097/00007435-198204000-00008.
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Single-dose treatment of gonococcal urethritis in males: evaluation of procaine penicillin, ampicillin and spectinomycin.男性淋菌性尿道炎的单剂量治疗:普鲁卡因青霉素、氨苄青霉素和壮观霉素的评估。
Can Med Assoc J. 1974 Jan 19;110(2):165-7.
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[On the problem of gonorrheal and postgonorrheal urethritis].
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[The level of penicillin in the blood serum during treatment of gonococcal infection with various doses of bicillin-3 and its combination with etamid].
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Piperacillin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.哌拉西林。对其抗菌活性、药代动力学特性及治疗用途的综述。
Drugs. 1984 Nov;28(5):375-425. doi: 10.2165/00003495-198428050-00002.
3
Comparison of piperacillin and penicillin in the treatment of uncomplicated gonorrhea.哌拉西林与青霉素治疗单纯性淋病的比较。
Antimicrob Agents Chemother. 1982 May;21(5):727-9. doi: 10.1128/AAC.21.5.727.
4
Single dose piperacillin in gonococcal urethritis.单剂量哌拉西林治疗淋菌性尿道炎
Genitourin Med. 1988 Apr;64(2):134-5. doi: 10.1136/sti.64.2.134-a.
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Single dose piperacillin in treating uncomplicated gonococcal urethritis in men.单剂量哌拉西林治疗男性单纯性淋菌性尿道炎
Genitourin Med. 1987 Oct;63(5):309-11. doi: 10.1136/sti.63.5.309.

本文引用的文献

1
Piperacillin therapy for serious bacterial infections.
Am J Med. 1980 Aug;69(2):255-61. doi: 10.1016/0002-9343(80)90386-1.
2
Piperacillin: human pharmacokinetics after intravenous and intramuscular administration.哌拉西林:静脉注射和肌肉注射后的人体药代动力学
Antimicrob Agents Chemother. 1978 Dec;14(6):829-37. doi: 10.1128/AAC.14.6.829.
3
In vitro antimicrobial activity of piperacillin and seven other beta-lactam antibiotics against Neisseria gonorrhoeae and Haemophilus influenzae, including beta-lactamase producing strains.哌拉西林及其他七种β-内酰胺类抗生素对淋病奈瑟菌和流感嗜血杆菌(包括产β-内酰胺酶菌株)的体外抗菌活性。
J Antimicrob Chemother. 1979 Mar;5(2):137-42. doi: 10.1093/jac/5.2.137.