Beighton D, Russell R R, Hayday H
J Gen Microbiol. 1981 Jun;124(2):271-9. doi: 10.1099/00221287-124-2-271.
A new serotype (h) of Streptococcus mutans was isolated from the dental plaque of monkeys (Macaca fascicularis). Serotype h strains fermented mannitol and melibiose but not sorbitol or raffinose, failed to hydrolyse aesculin and arginine, did not produce hydrogen peroxide and were unable to grow in the presence of bacitracin at 2 units ml-1. Sodium dodecyl sulphate-polyacrylamide gel electrophoresis of whole-cell proteins showed serotype h strains to be closely related to strains of genetic group III (i.e. serotypes d and g). The serotype-specific antigen of serotype h contained glucose and galactose but was antigenically distinct from the polysaccharide antigens of serotypes a, d and g. Serotype h strains preferentially colonized developmental grooves of teeth and the proportion of serotype h in the plaque flora was greater in monkeys fed a sucrose-rich diet than in monkeys fed a starch-based diet. A serotype h strain was cariogenic for germ-free rats fed a high-sucrose diet, and serotype h strains appear to be implicated in the caries process in monkeys.
从猕猴（食蟹猴）的牙菌斑中分离出变形链球菌的一种新血清型（h）。血清型h菌株能发酵甘露醇和蜜二糖，但不能发酵山梨醇或棉子糖，不能水解七叶苷和精氨酸，不产生过氧化氢，且在2单位/毫升杆菌肽存在的情况下无法生长。全细胞蛋白的十二烷基硫酸钠-聚丙烯酰胺凝胶电泳显示血清型h菌株与遗传组III的菌株（即血清型d和g）密切相关。血清型h的血清型特异性抗原含有葡萄糖和半乳糖，但在抗原性上与血清型a、d和g的多糖抗原不同。血清型h菌株优先定殖于牙齿的发育沟，在喂食富含蔗糖饮食的猕猴中，菌斑菌群中血清型h的比例高于喂食淀粉类饮食的猕猴。一株血清型h菌株对喂食高蔗糖饮食的无菌大鼠具有致龋性，血清型h菌株似乎与猕猴的龋齿过程有关。
